The proportion of contributors reporting at least just one adverse party was not impacted by dose, nor was the range with a significant adverse occasion, which was no more than with placebo.????? ??? ??????? ????? ???????? ???? ?????? ?? ????? ???????? ?? ????? ????????? ??? ??? ??????? ??????? ??? ????? ?? ???? ???? ???? ?? ??????? ???????:Side ef